Location: South San Francisco, CA
Position type: Full-time

Five Prime Therapeutics, Inc. (NASDAQ: FPRX)

is a publicly traded, clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics for patients with serious unmet medical needs. Five Prime has entered into strategic collaborations with leading global pharmaceutical companies and has promising product candidates in clinical and preclinical development.

We currently have three protein therapeutics in clinical trials:

  • FPA008: a monoclonal antibody that inhibits the CSF-1 receptor and is being studied in multiple tumor settings and pigmented villonodular synovitis (PVNS)
  • FPA144: a monoclonal antibody targeting FGFR2b for selected gastric cancers
  • FP-1039: a FGF ligand trap for mesothelioma

On the strength of our unique discovery platform and capabilities, we have entered into strategic collaborations with leading global pharmaceutical companies.  We currently have three active research collaborations with Bristol-Myers Squibb, GlaxoSmithKline and UCB Pharma, S.A.

Five Prime is committed to innovation and outstanding science to develop effective new drugs for the treatment of severe diseases. These values are reflected in our people and our products. We value our culture of openness, collaboration and productivity. Discover more about FivePrime at

The Position:

We are seeking a highly motivated Controller to join our Finance department in a fast-growing, dynamic and professional environment.  This position is responsible for overall day-to-day management of the accounting department, which includes financial reporting, financial information systems, accounts payable, payroll, treasury, fixed assets, and for ensuring proper internal controls are maintained. This position reports to the Chief Financial Officer.

The primary responsibilities include:

  • Provide strategic oversight on accounting operations and financial systems
  • Manage financial information systems monitoring and controls
  • Implement and enhance financial information systems as needed
  • Ensure that the monthly, quarterly and annual financial statements are completed on a timely basis and in accordance with GAAP
  • Responsible for the annual and quarterly financial statements for inclusion in the Company’s SEC reports
  • Coordinate corporate tax reporting and preparation of tax returns with outside tax accountants
  • Implement and ensure adherence to accounting policies and procedures
  • Maintain internal controls for key processes and SOX compliance
  • Participate in Audit Committee reporting and meeting
  • Review monthly journal entries and account reconciliations
  • Provide coaching and mentorship to help employees learn and grow in a changing environment
  • Represent Finance to partner with Legal, HR and IT on process evaluation and ongoing improvement projects
  • Other duties as mutually agreed upon to make this position a career building experience


  • BA/BS degree in finance, economics or accounting
  • CPA license required
  • 15+ years of experience; biotechnology-type industry experience preferred
  • Experience with a Big Four certified public accounting firm is highly preferred
  • Proven experience working for a publicly-traded company is required
  • Thorough knowledge of SEC rules and regulations, procedures and practices
  • Excellent knowledge of ERP systems
  • Excellent written and interpersonal skills; ability to interface and communicate effectively with executive management and other functions within the organization
  • Strong team leadership, management, and organizational skills
  • Ability to use critical thinking and good business sense to make good business decisions
  • Proven experience on building team and resolving conflicts in a collaborative manner
  • Detail-oriented and positive “can-do” attitude towards assigned responsibilities

Please upload your cover letter and resume

Apply Here