Five Prime is pursuing discovery and clinical development of its product candidates both independently and in collaboration with pharmaceutical partners. This approach has been successful – to date, we have received approximately $307 million under collaboration arrangements, with potential for additional milestone and royalty payments – and it has allowed us to bolster the capital resources needed to build our drug discovery platform while also expanding our pipeline of product candidates.
We are currently focused on therapies for cancer and inflammatory diseases for our own pipeline. Three drug candidates in these areas have progressed into active or imminent human clinical trials. We are also focusing our earlier stage research efforts on cancer immunotherapy.