Management

Lewis T. "Rusty" Williams, M.D., Ph.D.

Founder, President and CEO

Dr. Williams founded the company in December 2001 and has served as a member of our board of directors since January 2002, as our President and Chief Executive Officer since August 2011, and as our Executive Chairman from July 2003 to January 2012. Previously, Dr. Williams spent seven years at Chiron Corporation, a biopharmaceutical company, now Novartis Vaccines and Diagnostics, Inc., most recently as its Chief Scientific Officer. He also served on Chiron’s board of directors from 1999 to 2001. Prior to joining Chiron, Dr. Williams was a professor of medicine at the University of California, San Francisco and served as director of the University’s Cardiovascular Research Institution and Daiichi Research Center. Dr. Williams also has served on the faculties of Harvard Medical School and Massachusetts General Hospital and co-founded COR Therapeutics, Inc., a biotechnology company focused on cardiovascular disease. He is a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. Dr. Williams was previously a member of the boards of directors of COR Therapeutics, Inc. and Beckman Coulter, Inc., each of which was a public company. Dr. Williams received a B.S. from Rice University and an M.D. and a Ph.D. from Duke University.

Julie Hambleton, M.D.

Senior Vice President and Chief Medical Officer

Dr. Hambleton has served as our Senior Vice President and Chief Medical Officer since December 2012. From April 2010 to December 2012, Dr. Hambleton served as Vice President, Clinical Development, at Clovis Oncology, Inc., a public biopharmaceutical company. From 2003 to April 2010, Dr. Hambleton served at Genentech, Inc., a biotechnology company acquired by Hoffman-LaRoche AG, in positions of increasing responsibility, most recently as Group Medical Director, Global Clinical Development from July 2009 to April 2010. Prior to 2003, Dr. Hambleton served for 10 years in academic positions in the Division of Hematology/Oncology at the University of California, San Francisco, most recently as Associate Professor of Clinical Medicine. Dr. Hambleton received a B.S. from Duke University and an M.D. from Case Western Reserve University School of Medicine. She is Board Certified in Hematology and Internal Medicine.

W. Michael Kavanaugh, M.D.

Senior Vice President and Chief Scientific Officer

Dr. Kavanaugh has served as our Senior Vice President and Chief Scientific Officer since January 2013. From February 2009 to January 2013, Dr. Kavanaugh served as our Senior Vice President, Research and Development. Previously, Dr. Kavanaugh served at Novartis Vaccines and Diagnostics, Inc., a healthcare company, in positions of increasing responsibility, most recently as Vice President of Novartis Vaccines & Diagnostics, Inc. and Executive Director of Novartis Institutes of Biomedical Research from 2006 to February 2009. Novartis Vaccines and Diagnostics, Inc. was formerly known as Chiron Corporation before its acquisition in 2006. Dr. Kavanaugh also currently serves as an Attending Staff Physician, Coronary Intensive Care Unit at the San Francisco Veterans Administration Medical Center and as an Associate Clinical Professor of Medicine at the University of California, San Francisco. Dr. Kavanaugh received a B.S. in Molecular Biochemistry and Biophysics from Yale University and an M.D. from Vanderbilt University. He trained in Internal Medicine, Cardiovascular Disease and Molecular and Cellular Biology at the University of California, San Francisco and the Cardiovascular Research Institute. He is Board Certified in Cardiovascular Disease and Internal Medicine.

Marc Belsky

Senior Vice President and Chief Financial Officer

Mr. Belsky has served as our Vice President and Chief Financial Officer since October 2013. From October 2009 to October 2013 he served as our Vice President, Finance. From December 2006 to October 2009, Mr. Belsky served as Vice President, Finance, and Chief Accounting Officer of Cell Genesys, Inc., a biotechnology company acquired by BioSante Pharmaceuticals, Inc. Prior to 2006, Mr. Belsky served as Vice President, Global Visa Commerce at Visa Inc., Chief Financial Officer at Active Aero Group, Inc. and Chief Financial Officer at DataWave Systems Inc. Prior to these positions, he served for 15 years at Michigan National Corporation, a holding company for Michigan National Bank which was acquired by BANA Holding Corporation, in positions of increasing responsibility, most recently as Senior Vice President, U.S. Payment Products and Services. Mr. Belsky started his career as an auditor with Coopers & Lybrand. Mr. Belsky received a B.S. in Accounting from Wayne State University and an M.B.A. from University of Michigan. He is a certified public accountant, a chartered global management accountant and a certified treasury professional.

Aron Knickerbocker

Senior Vice President and Chief Business Officer

Mr. Knickerbocker has served as our Senior Vice President and Chief Business Officer since April 2012 and as a member of our board of directors since October 2013. From September 2009 to April 2012, he served as our Vice President, Business Development. From 2001 to September 2009, Mr. Knickerbocker served at Genentech, Inc. in positions of increasing responsibility most recently as Senior Director, Business Development from 2005 to September 2009. Prior to 2001, Mr. Knickerbocker served as Director of Commercial Development at ALZA Corporation, a pharmaceutical company acquired by Johnson & Johnson, as Senior Manager, Corporate Development at Amgen Inc., a public biotechnology company and as a scientist at Bristol-Myers Squibb Company, a public biopharmaceutical company. Mr. Knickerbocker received an A.B. in biology from Washington University in St. Louis and an M.B.A. from the University of Michigan.

Francis Sarena

Senior Vice President, General Counsel and Secretary

Mr. Sarena has served as our Senior Vice President since January 2013, and as General Counsel and Secretary since December 2010. Mr. Sarena also served as Vice President from December 2010 to January 2013. From December 2008 to July 2010, Mr. Sarena served as Vice President, General Counsel and Secretary of Facet Biotech Corporation, a public biotechnology company that was spun off from PDL BioPharma, Inc. and was later acquired by Abbott Laboratories. From April 2006 to December 2008, Mr. Sarena served at PDL BioPharma, Inc. in positions of increasing responsibility, most recently as Vice President, General Counsel and Secretary from June 2008 to December 2008. Prior to 2006, Mr. Sarena served as an associate at Bingham McCutchen LLP where he represented public and private life science and high tech clients primarily in merger and acquisition transactions, corporate and securities law matters and equity financing transactions. Mr. Sarena received a B.S. in Finance from San Francisco State University and a J.D. from University of California, Berkeley.

Kevin P. Baker, Ph.D.

Vice President, Preclinical Development

Dr. Baker has served as our Vice President, Preclinical Development, since January 2006. From 1999 to 2006, Dr. Baker served in positions of increasing responsibility at Human Genome Sciences, Inc., a biopharmaceutical company acquired by GlaxoSmithKline, most recently as Associate Director, Protein Therapeutics. From 1992 to 1999, Dr. Baker served as a Scientist at Genentech, Inc., a biotechnology company acquired by Roche Holding Ltd. Dr. Baker received a B.Sc. in Biochemistry and Physiology from the University of Salford, England, and a Ph.D. from the University of Dundee, Scotland.

Lauretta Cesario

Vice President, Human Resources

Ms. Cesario has served as our Vice President, Human Resources, since August 2009. From 2001 to 2006, Ms. Cesario served as Vice President, Human Resources at Affymetrix, Inc. From 1997 to 2001, Ms. Cesario served as Vice President, Human Resources at Scios, Inc. Prior to 1997, Ms. Cesario served for 18 years in human resources positions of increasing scope and responsibility at Silicon Graphics, Inc., National Semiconductor Corporation, Syntex Corporation and Bank of America. Ms. Cesario received a B.S. in Psychology from Loyola University.

Robert Sikorski, M.D., Ph.D.

Vice President, Global Clinical Development

Dr. Sikorski has served as our Vice President, Global Clinical Development, since September 2014. From December 2010 to September 2014, Dr. Sikorski served as Senior Director, Global Oncology Research and Development at Medimmune, LLC, a biotechnology company acquired by AstraZeneca, PLC. From March 2006 to December 2010, Dr. Sikorski served as Director, Global Oncology Research and Development at Amgen Inc., a biopharmaceutical company. From 2004 to 2006, Dr. Sikorski served as a consultant to Genzyme Corporation, a biotechnology company. From 1999 to 2003, Mr. Sikorski served as the Chief Technology Officer of Mednav, Inc., a biomedical data acquisition and analytics company.Dr. Sikorski began his career as a Howard Hughes Research Fellow and Visiting Scientist at the National Cancer Institute and the National Human Genome Research Institute in the laboratory of Nobel Laureate, Harold Varmus. Dr. Sikorski received a B.S. from The Pennsylvania State University, and an M.D. and a Ph.D. in Biochemistry and Cellular and Molecular Biology from The Johns Hopkins University School of Medicine. He is Board Certified in Medical Oncology and Internal Medicine.

Brian Wong, M.D., Ph.D.

Vice President, Research and Head of Cancer Immunotherapy

Dr. Wong has served as our Vice President, Biology, since January 2009. From 2005 to 2009, Dr. Wong served as Director of Research in the inflammation disease biology area at Roche Palo Alto. From 2000 to 2005, Dr. Wong served as Associate Director, Experimental Physiology, at Rigel Pharmaceuticals, Inc. Dr. Wong received a B.A. in Chemistry and Biochemistry from Oberlin College, a Ph.D. from The Rockefeller University and an M.D. from the Weill Cornell Medical College of Cornell University.