A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Director, Antibody Engineering

Senior Scientist/Scientist III - Immuno-Oncology

Research Associate II – III, Protein Chemistry

Research Associate I, II – Immuno-Oncology Discovery

Preclinical Development

Director, Bioanalytical Development

Senior Manager / Manager, Supply Chain Management

Scientist I, II – Pharmacology/Tumor Immunology

Research Associate – Pharmacology/Oncology

Clinical Development

Senior Director - Clinical Operations

Senior Director – Project Team Leader

Senior Medical Director / Medical Director, Clinical Development

Director Clinical Scientist

Senior Scientist – Translational Oncology

Clinical Trial Manager - Clinical Operations

Project Manager – Clinical Development

Senior Administrative Assistant – Clinical Development & Regulatory

Business Development

Senior Director, Investor Relations and Corporate Communications


Patent Paralegal / Senior Patent Paralegal