A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

If you want to help bring the next generation of biologics to the medical community and the world’s patients look no further than Five Prime.  We are here to bring medicines to life!

Diversity & Inclusion

FivePrime is an equal opportunity employer committed to a diverse workforce. FivePrime makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.

Notice to Recruiters and Agencies

Five Prime acknowledges that providers may be a valuable resource for identifying and recruiting candidates for employment.  However, we require that all recruiters engage directly with Five Prime’s Talent Acquisition Team and comply with Five Prime’s requirements prior to transmitting any resumes/CVs or introducing any candidates to Five Prime.  Five Prime’s Talent Acquisition Team is the only function within the Company that can enter into contractual relationships with external recruiters and recruiting agencies.   As such, all unsolicited resumes, CVs, anonymous profiles, or candidate information you may submit to employees of Five Prime will become property of Five Prime and Five Prime will have no obligation to pay you or anyone else for the use of such information, including any finder’s, placement, introduction or placement fee.

Five Prime’s Talent Acquisition Team manages the sourcing, recruitment and engagement of candidates for employment. Five Prime requires that recruiters enter into a signed agreement with Five Prime prior to submitting any candidate resumes/CVs or other candidate information for consideration. Submission of unsolicited resumes in advance of a signed agreement between Five Prime and a recruiter will not create any implied obligation on the part of Five Prime.

If you are interested in developing a recruiting relationship with us, you must work directly with Five Prime’s Talent Acquisition Team. For more details, please send an email to

Current Opportunities


Scientist II - III, Immuno-Oncology Research

Scientist I-II, Antibody Engineering & Technologies

Research Associate lll / IV, Immuno-Oncology Research

Research Associate III-IV, Immuno-Oncology Research (Validation)

Research Associate I-II, Molecular Biology

Development Sciences

Director / Senior Director, Pathology

Scientist III / Senior Scientist, Upstream Process Development

Manager, Formulation (Stability)

Scientist l, Formulation

Research Associate I-II, Analytical Development

Clinical Development & Regulatory Affairs

Associate Director / Director, Drug Safety

Clinical Program Manager / Senior Clinical Program Manager

Clinical Outsourcing Manager/Senior Clinical Outsourcing Manager

Senior Research Specialist / Scientist I, Clinical Biomarkers & CDx Dev

Senior Clinical Trial Manager

Senior Clinical Trial Manager (Contract)

Senior Medical Writer, Regulatory Affairs

Clinical Trial Manager I

Clinical Trial Manager II

Clinical Data Manager (Contract)

Clinical Biosample Manager

Clinical Biosample Manager (Contract)


Senior Accountant

Executive Assistant (Finance & IR)


Associate Director / Director, GCP Compliance

Systems Engineering & Information Technology

IT Business Systems Analyst

Software Engineer I

IT Help Desk Associate