A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Scientist III / Senior Scientist, Immuno-Oncology Research

Research Associate / Senior Research Specialist, Antibody Engineering and Technologies

Research Associate I-II, Immuno-Oncology Research

Research Associate, Protein Chemistry

Research Associate, Immuno-Oncology Discovery (2 positions)

Development Sciences

Director, Pharmacology

Scientist I-II, Pharmacology

Scientist I-II, Cell Line and Cell Culture, Process Development

Scientist I-III, Bioanalytical Development

Scientist I-III, Biomarker and Clinical Diagnostic Development

Research Associate / Senior Research Specialist, Process Development

Research Associate, Cell Line Development (Temp)

Clinical Development

Senior Manager / Associate Director, Regulatory Affairs

Clinical Trial Manager II

Clinical Trial Manager / Senior Clinical Trial Manager

Business Operations

Director, Compensation, Benefits & HRIS

Project Manager / Senior Project Manager

Corporate Counsel

Manager / Senior Manager, Quality Assurance

Document Control Specialist

Payroll Accountant / Senior Payroll Accountant

Accounts Payable Specialist

IT Helpdesk Associate

Buyer I