A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Director, Antibody Engineering

Senior Scientist/Scientist III - Immuno-Oncology

Scientist I, II – Immunology

Research Associate III – IV, Protein Chemistry

Research Associate II, III – Antibody Therapeutics

Research Associate II, III – Immuno-Oncology Discovery (2 Positions)

Temporary Research Associate II, III – Immuno-Oncology Validation

Temporary Automation Associate - Systems Engineering

Preclinical Development

Senior Director / Director – Clinical Biomarker & Companion Diagnostics Development

Director, Bioanalytical Development

Manager, Supply Chain Management

Scientist I, II – Pharmacology/Tumor Immunology

Research Associate – Analytical Development

Research Associate II, III – Pharmacology/Oncology

Research Associate II, III – Process Development

Temporary Research Associate – Pharmacology

Clinical Development

Senior Director - Clinical Operations

Senior Director – Project Team Leader

Senior Medical Director / Medical Director, Clinical Development

Director/Associate Director Clinical Scientist

Clinical Trial Manager - Clinical Operations

Project Manager – Clinical Development (Part-Time)

Senior Administrative Assistant – Clinical Development & Regulatory


Vice President - Regulatory Affairs

Temporary Regulatory Operations Specialist


Patent Paralegal / Senior Patent Paralegal