A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Senior Scientist, Protein Chemistry

Research Associate, Immuno-Oncology Discovery (2 positions)

Development Sciences

Scientist II-III, Clinical Biomarkers and CDx Development

Scientist I-II, Pharmacology

Senior Research Specialist / Scientist l, Analytical Development

Sr. Research Specialist, Bioanalytical Development

Clinical Development & Regulatory Affairs

Senior Director, Drug Safety

Associate Director / Director, Clinical Development

Associate Director, Regulatory Affairs

Senior Manager / Associate Director, Clinical & Statistical Programming

Clinical Biosample Manager

Clinical Data Manager

Clinical Program Manager

Senior Clinical Trial Manager

Senior Clinical Trial Manager (Contract)



Associate Director, Corporate Accounting

Human Resources

Recruitment Manager


Clinical Contracts Associate / Manager


Director, Marketing Strategy


Associate Director / Director, GCP Compliance

Systems Engineering & Information Technology

Senior Engineer / Manager, Computer Systems Validation

IT Systems Analyst