A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Research Associate, Protein Chemistry

Senior Research Specialist, Antibody Engineering & Technologies

Development Sciences

Director, Clinical Biomarkers & CDx Development, Biomarker Biology and Translation

Senior Manager/ Associate Director, Contract Manufacturing Organization (CMO) Management

Scientist II-III, Clinical Biomarkers and CDx Development

Scientist III, Pharmacology

Scientist I-II, Pharmacology

Sr. Research Specialist, Bioanalytical Development

Clinical Development & Regulatory Affairs

Associate Director, Regulatory Affairs

Senior Manager / Associate Director, Clinical & Statistical Programming

Senior Biostatistician (Contract)

Senior Drug Safety Associate

Clinical Program Manager

Senior Clinical Trial Manager

Senior Clinical Trial Manager (Contract)

Corporate Administration

Executive Assistant , Chief Operating Officer

Project Management

Director / Sr. Director, Project Management


Director, Marketing Strategy


Associate Director / Director, GCP Compliance

Systems Engineering & Information Technology

IT Manager, Computer Systems Compliance

IT Systems Analyst