A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

FivePrime is an equal opportunity employer committed to a diverse workforce. FivePrime makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


VP, Immuno-Oncology Research

Scientist lll / Senior Scientist, Molecular Biology

Scientist II - III, Immuno-Oncology Research

Scientist l - ll, Protein Chemistry

Senior Research Specialist, Protein Chemistry

Research Associate lll / IV, Immuno-Oncology Research

Research Associate I-II, Molecular Biology

Development Sciences

Scientist III / Senior Scientist, Upstream Process Development

Senior Research Specialist / Scientist I, Clinical Biomarkers & CDx Dev

Clinical Development & Regulatory Affairs

Executive Director/ Vice President, Clinical Development

Senior Director, Biometrics

Associate Director / Director, Clinical Development

Associate Director / Director, Drug Safety

Clinical Program Manager / Senior Clinical Program Manager

Senior Clinical Trial Manager

Senior Clinical Trial Manager (Contract)

Senior Medical Writer, Regulatory Affairs

Clinical Trial Manager I

Clinical Trial Manager II

Clinical Data Manager

Clinical Data Manager (Contract)

Clinical Biosample Manager (Contract)


Manager/ Sr. Manager, FP&A (Financial Planning & Analysis)

Senior Accounts Payable Specialist


Associate Director / Director, GCP Compliance

Systems Engineering & Information Technology

IT Business Systems Analyst

IT Help Desk Associate