A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Research Associate, Protein Chemistry

Development Sciences

Director, Clinical Biomarkers & CDx Development, Biomarker Biology and Translation

Director, Clinical Biomarkers & CDx Development, Biomarker Testing and Analysis

Director, Pharmacology

Scientist II-III, Formulation

Scientist III, Pharmacology

Scientist I-II, Pharmacology

Scientist I-III, Bioanalytical Development

Manager, Formulation (Stability)

Research Associate III-IV / Senior Research Specialist, Translational Biology and Clinical Biomarkers

Research Associate, Pharmacology

Clinical Development & Regulatory Affairs

Senior Manager / Associate Director, Regulatory Affairs

Clinical Program Manager

Senior Clinical Trial Manager

Senior Clinical Trial Manager (Contract)

Human Resources

Director, Compensation, Benefits & HRIS

Project Management

Director / Sr. Director, Project Management

Project Manager / Senior Project Manager


Associate Director / Director, GCP Compliance

Systems Engineering & Information Technology

Intern / Co-Op Student, Automation Engineering

Intern / Co-Op Student, Software Engineering