A position at Five Prime is more than just a job; it’s an opportunity to join a group of entrepreneurial employees committed to developing innovative protein therapeutics that can improve the lives of patients. We seek candidates who value scientific innovation, entrepreneurial spirit and teamwork.

We are actively recruiting for a variety of positions throughout the company and welcome inquiries from people who want to help bring the next generation of biologics to the medical community and the world’s patients.  In addition to email, we can be reached at:

Five Prime Therapeutics, Inc. 
Attn: Recruiting Coordinator
Two Corporate Drive
South San Francisco, CA 94080

Notice to Recruiters and Agencies

We prefer to first recruit candidates directly, rather than through a third-party recruiter or agency. Blinded CVs and resumes of qualified candidates will be reviewed and considered for advertised positions only, with follow-up initiated by us. In the case of candidate(s) submitted or presented to us by a recruiter or agency without a signed agreement, we explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.

Current Opportunities


Senior Scientist/Scientist - Antibody Therapeutics

Scientist I - III, Immuno-Oncology Research and Exploratory Biomarkers

Research Associate - Protein Chemistry

Research Associate I - Molecular Biology

Preclinical Development

Director, Tumor Immunology/Pharmacology

Director, Cell Culture Bioprocess Development

Vivarium Manager

Scientist I - Tumor Immunology/Pharmacology

Senior Research Specialist/Research Associate IV - Cell Line and Cell Culture-Process Development

Senior Research Specialist/Research Associate IV - Biomarker and Clinical Diagnostic Development

Clinical Development

Senior Medical Director / Medical Director, Clinical Development

Senior Clinical Trial Manager

Senior Project Manager/ Project Manager

Clinical Biosample Manager – Clinical Operations

Regulatory Operations Associate


Facilities Assistant

Human Resources

Director, Human Resources